泰诺福韦

泰诺福韦

泰诺福韦

编号ABP000917 化学名称Tenofovir,TDF,PMPA/ CAS147127-20-6 MDL: MFCD00943794 分子式C9H14N5O4P 分子量287.215 纯度 >99%

化学名称 : 泰诺福韦

CAS : 147127-20-6

英文名称: Tenofovir,TDF,PMPA/

英文同义词: TENOFOVIR

溶解度:DMSO

储存条件:at -20℃ 2 years

生物活性

Previously the IN substitutions V75I, Q148R, V151I, and G163R were reported as being associated with BMS-707035 resistance [48] , although no indication was given as to the resistance severity associated with each substitution. BMS-707035 is an HIV-1 integrase (IN) inhibitor. BMS-707035 was scheduled to be evaluated in a Phase II study to assess the antiretroviral activity, safety, pharmacodynamics, and pharmacokinetics in 50 HIV-infected subjects using a 10-day randomized, double-blind, placebo-controlled, ascending multiple-dose study design

参考文献

Laith Q Al-Mawsawi et al. Expert Opinion on Emerging Drugs. 2008 June;13(2):213-225

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