LY2779357/

Storage:at -20℃ 2 years

Biologieal

LY2940680 has been shown to affect a cancer cell signaling pathway initiated by the Hedgehog (Hh) protein, which is essential for regulating normal cell differentiation and proliferation.  Abnormal Hh signaling has been implicated in several types of cancer, including brain, lung, breast, prostate and skin cancers.  Abnormal Hh pathway activation can result from genetic mutations in the pathway's protein components

Reference

LY2940680: Halting Abnormal Signaling via the Hedgehog Pathway (Abstract # 2819)