WP1130

WP1130

WP1130

编号ABP000853 化学名称WP1130 CAS856243-80-6 分子式C19H18BrN3O 分子量384.27 纯度 >99%

化学名称 : WP1130

CAS : 856243-80-6

英文名称: WP1130

英文同义词: (2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]-2-propenamide

溶解度:DMSO

储存条件:at -20℃ 2 years

生物活性

FG-4592, received Clinical Trial Application (CTA) approval from the Chinese State Food and Drug Administration (SFDA) to commence clinical development for the treatment of anemia associated with chronic kidney disease (CKD) in the People's Republic of China. FG-4592 is a first-in-class hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor (PHI) entering Phase 2b clinical development in the US and Europe for the treatment of CKD anemia. SFDA approved protocols for both Phase 1 and 2 studies. The first of these studies of FG-4592 in China will begin in the fourth quarter of 2010.

参考文献

FG-4592 oral anemia therapy receives CTA approval from SFDA

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