TROX-1/

TROX-1/

TROX-1/

编号ABP000834 化学名称TROX-1/ 分子式 分子量0.0

化学名称 : TROX-1/

CAS :

英文名称: TROX-1/

英文同义词:

溶解度:Unknown

储存条件:at -20℃ 2 years

生物活性

INCB018424 is an orally bioavailable JAK inhibitor with potential antineoplastic and immunomodulating activities. INCB018424, a characterized JAK1/JAK2 inhibitor (IC50 values for JAK1, JAK2 and JAK3 are 3, 5 and 332 nM, respectively), has reached clinical trials for oncology indications, rheumatoid arthritis, and psoriasis. This compound is worth noting due to its opposite potency profile in the inhibition of the JAK enzymes when compared to CP-690,550.

参考文献

[1] http://www.cancer.gov/drugdictionary/?CdrID=593437

询价