化学名称 : VX-809/VX809
CAS : 936727-05-8
英文名称: VX-809/VX809
英文同义词: VX-809
溶解度:Unknown
储存条件:at -20℃ 2 years
生物活性
VX-809 may act to restore the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, the defective cell membrane protein responsible for the progression of CF. Defects in the CFTR protein affect the transport of chloride and other ions across cells, and lead to the accumulation of thick, sticky mucus in the lungs of patients with CF. This mucus fosters chronic infection and inflammation, and results in irreversible lung damage.