阿吡莫德
编号ABP000484
化学名称STA 5326
CAS541550-19-0
MDL: MFCD09954108
分子式C23H26N6O2
分子量418.498
纯度 98%
化学名称 : 阿吡莫德
CAS : 541550-19-0
英文名称: STA 5326
英文同义词: APILIMOD
同义词: 3-甲基-2-[6-(4-吗啉基)-2-[2-(2-吡啶基)乙氧基]-4-嘧啶基]肼苯甲醛
溶解度:Unknown
储存条件:at -20℃ 2 years
生物活性
Potent and orally active inhibitor of the cytokines interleukin-12 (IL-12), and interleukin-23 (IL-23) production; potential regulators of certain autoimmune and inflammatory diseases.
参考文献
Wada et al: Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor. Blood, 2007, 109(3), 1156-1164. Wada et al: IL-12/IL-23 inhibitors: a promising approach to the treatment of inflammatory disorders. Drugs Fut. 2008, 33(1), 49-63.
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Bencynoate hydrochloride/
162220-36-2
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PF-477736
952021-60-2
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磺胺苯吡唑
526-08-9
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醋酸羟孕酮
302-23-8
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