MDV3100/MDV-3100

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MDV3100/MDV-3100

MDV3100/MDV-3100

编号ABP000459 化学名称MDV3100/MDV-3100 CAS915087-33-1 MDL: MFCD14155804 分子式C21H16F4N4O2S 分子量464.441 纯度 >99%

化学名称 : MDV3100/MDV-3100

CAS : 915087-33-1

英文名称: MDV3100/MDV-3100

英文同义词: MDV3100

同义词: MDV3100

Solubility:DMSO

Storage:at -20℃ 2 years

Biologieal

MDV3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. It also induces tumour cell apoptosis, and has no agonist activity.

Reference

[1] Prof Howard I Scher MD et al. The Lancet. 2010 April; 375(9724): 1437-1446

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