化学名称 : SB408124/SB-408124/
CAS : 288150-92-5
英文名称: SB408124/SB-408124/
英文同义词: N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea
溶解度:Soluble to 100 mM in DMSO
储存条件:Store at RT
生物活性
Selective non-peptide orexin OX1 receptor antagonist (Kb values are 21.7 and 1405 nM for human OX1 and OX2 receptors respectively). Blocks orexin-A induced grooming following oral administration in vivo.