主页 / 产品目录 / Activator / STF-62247/STF62247


编号ABP000372 化学名称STF-62247/STF62247 CAS315702-99-9 分子式C15H13N3S 分子量267.349 纯度 99%

化学名称 : STF-62247/STF62247

CAS : 315702-99-9

英文名称: STF-62247/STF62247

英文同义词: N-(3-Methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine

溶解度:Soluble in DMSO up to 26mg/ml

储存条件:-20C 2 years


Kill kidney cancer cells, Novel Breakthrough. STF-62247 is a selective inducer of autophagy in VHL-deficient renal cell carcinoma cells by inducing cytotoxicity and reducing tumor growth.


1, Turcotte S, A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. Cancer Cell. 2008 Jul 8;14(1):90-102. 2, Turcotte S,Targeted therapy for the loss of von hippel-lindau in renal cell carcinoma: A novel molecule that induces autophagic cell death. Autophagy. 2008 Oct 13;4(7).