SU-11274/SU11274,PKI-SU11274

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SU-11274/SU11274,PKI-SU11274

SU-11274/SU11274,PKI-SU11274

编号ABP000133 化学名称SU-11274/SU11274,PKI-SU11274 CAS658084-23-2 分子式C28H30ClN5O4S 分子量568.087 纯度 97%

化学名称 : SU-11274/SU11274,PKI-SU11274

CAS : 658084-23-2

英文名称: SU-11274/SU11274,PKI-SU11274

英文同义词: (3Z)-N-(3-Chlorophenyl)-3-[[3,5-dim ethyl-4-[(4-methyl-1-piperazinyl)carbonyl]-1H-pyrr ol-2-yl]methylene]-2,3-dihydro-N-methyl-2-oxo-1H-i ndole-5-sulfonamide

溶解度:Soluble in DMSO 10 mg/ml at 60

储存条件:Store at -20°C

生物活性

Selective inhibitor of MET tyrosine kinase activity (IC50 = 0.01 μM in vitro). Reduces cell growth in a dose-dependent manner; induces cell cycle arrest and apoptosis. Abrogates cell motility and migration in vitro and tumor angiogenesis in vivo.
询价