852475-26-4

MC1568/MC-1568

852475-26-4

编号ABP000149 化学名称MC1568/MC-1568 英文名称 MC1568/MC-1568 MDL: MFCD16875423 分子式C17H15FN2O3 分子量314.315 纯度 >99%

化学名称 : MC1568/MC-1568

CAS : 852475-26-4

英文名称: MC1568/MC-1568

英文同义词: 3-[5-(3-(3-Fluorophenyl)-3-oxopropen-1-yl)-1-methyl-1h-pyrrol-2-yl]-n-hydroxy-2-propenamide;MC1568

溶解度:DMSO

储存条件:at -20

生物活性

MC1568 is a potent selective class II (IIa) histone deacetylas (HDAC II) inhibitor (IC50 of a maize deacetylase HD2 at 22.0 µM). MC1568 had no or a weak effect on the class I HDACs. MC1568 shows no inhibitory activity against HDAC1 but was able to inhibit HDAC4. [1, 2]

参考文献

[1] Duong V et al. Mol Cancer Res. 2008 Dec; 6(12):1908-19

询价