化学名称 : Fesoterodine fumarate/
CAS : 286930-03-8
英文名称: Fesoterodine fumarate/
英文同义词: FESOTERODINE MALEATE
溶解度:Unknown
储存条件:at -20℃ 2 years
生物活性
Urapidil α1-adrenoceptor antagonist and 5-HT1A receptor agonist (pIC50 values are 6.13 and 6.4 respectively). Clinically used hypotensive agent.
参考文献
Gross et al (1987) Urapidil and some analogues with hypotensive properties show high affinities for 5-hydroxytryptamine (5-HT) binding sites of the 5-HT1A subtype and for a1-adrenoceptor binding sites. Naunyn-Schmied.Arch.Pharmacol. 336 597. van Zwieten (1989) Pharmacologic profile of urapidil. Am.J.Cardiol. 64 1D. Kolassa et al (1989) Involvement of brain 5-HT1A receptors in the hypotensive response to urapidil. Am.J.Cardiol. 64 7D.