146426-40-6

Flavopiridol(Alvocidib)/HMR-1275,L868275

146426-40-6

编号ABP000848 化学名称Flavopiridol(Alvocidib)/HMR-1275,L868275 英文名称 Flavopiridol(Alvocidib)/HMR-1275,L868275 MDL: MFCD00894265 分子式C21H20ClNO5 分子量401.844 纯度 >98%

化学名称 : Flavopiridol(Alvocidib)/HMR-1275,L868275

CAS : 146426-40-6

英文名称: Flavopiridol(Alvocidib)/HMR-1275,L868275

英文同义词: FLAVOPIRIDOL

溶解度:Unknown

储存条件:at -20℃ 2 years

生物活性

AT7519 is a novel small molecule multi-cyclin-dependent kinase inhibitor. It selectively binds to and inhibits cyclin dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. CDKs are serine/theronine kinases involved in regulation of the cell cycle and may be overexpressed in some types of cancer cells. [1][2]

参考文献

[1] Santo L et al. Oncogene. 2010 Apr 22;29(16):2325-36

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