化学名称 : BIX 02189/BIX02189
CAS : 1094614-85-3
英文名称: BIX 02189/BIX02189
英文同义词: 3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-N,N-dimethyl-2-oxo-1H-indole-6-carboxamide
溶解度:Soluble in DMSO at 20 mg/mL
储存条件:Storage at -20C 2 years
生物活性
A MEK5-selective inhibitor, completely reversed the inhibitory effects of flow.
参考文献
ERK5 Activity Is Required for Nerve Growth Factor-induced Neurite Outgrowth and Stabilization of Tyrosine Hydroxylase in PC12 Cells Identification of pharmacological inhibitors of the MEK5/ERK5 pathway.