UK383367/UK-383367

 Home / Products / Inhibitors / Other inhibitors / UK383367/UK-383367
UK383367/UK-383367

UK383367/UK-383367

Cat.No.ABP000934 Chemical NameUK383367/UK-383367 CAS348622-88-8 MDL: MFCD19443866 MolFormulaC15H18N4O4 MolWeight318.331 Purity >99%

Chemical Name : UK383367/UK-383367

CAS : 348622-88-8

Synonyms: UK 383367

Solubility:DMSO

Storage:at -20℃ 2 years

Biologieal

Tipifarnib (Zarnestra, R115777, IND 58359) is a farnesyltransferase inhibitor (IC50=0.6 nM) that is used in patients 65 years of age and older with newly diagnosed acute myeloid leukemia (AML). It is also being tested in clinical trials in patients in certain stages of breast cancer. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction.

Reference

[1] http://en.wikipedia.org/wiki/Tipifarnib

Enquiry