BIX 02189/BIX02189

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BIX 02189/BIX02189

BIX 02189/BIX02189

Cat.No.ABP000923 Chemical NameBIX 02189/BIX02189 CAS1094614-85-3 MolFormulaC27H28N4O2 MolWeight440.5368 Purity >99%

Chemical Name : BIX 02189/BIX02189

CAS : 1094614-85-3

Synonyms: 3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-N,N-dimethyl-2-oxo-1H-indole-6-carboxamide

Solubility:Soluble in DMSO at 20 mg/mL

Storage:Storage at -20C 2 years

Biologieal

A MEK5-selective inhibitor, completely reversed the inhibitory effects of flow.

Reference

ERK5 Activity Is Required for Nerve Growth Factor-induced Neurite Outgrowth and Stabilization of Tyrosine Hydroxylase in PC12 Cells Identification of pharmacological inhibitors of the MEK5/ERK5 pathway.

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