Chemical Name : PD153035 hydrochloride/
CAS : 153436-54-5
Synonyms: PD 153035 HYDROCHLORIDE
Solubility:Soluble in DMSO at 10 mmol/L
Storage:-20C 2 years
Pazopanib (GW-786034) is a second-generation multitargeted tyrosine kinase inhibitor against VEGFR-1, 2 and 3, platelet-derived growth factor receptor (PDGFR)-, PDGFR-ß and c-kit.
1. Pazopanib, a potent orally administered small-molecule multitargeted tyrosine kinase inhibitor for renal cell carcinoma. Sonpavde, G., Hutson, T.E., et al. Volume 17, Issue 2, February 2008, Pages 253-261
2. Pazopanib: a novel multitargeted tyrosine kinase Inhibitor. Guru Sonpavde, Thomas E. Hutson. 2007 Current Oncology Reports 9 (2), pp. 115-119