AT-7519(HCI)/

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AT-7519(HCI)/

AT-7519(HCI)/

Cat.No.ABP000844 Chemical NameAT-7519(HCI)/ MolFormula MolWeight0.0

Chemical Name : AT-7519(HCI)/

CAS :

Solubility:Soluble in DMSO

Storage:-20C 2 years

Biologieal

PHA-848125 is an orally bioavailable inhibitor of cyclin-dependent kinases (CDKs) and thropomyosin receptor kinase A (TRKA), with potential antineoplastic activity.

Reference

Dual Targeting of CDK and Tropomyosin Receptor Kinase Families by the Oral Inhibitor PHA-848125, an Agent with Broad-Spectrum Antitumor Efficacy By Albanese, Clara; Alzani, Rachele; Amboldi, Nadia; Avanzi, Nilla; Ballinari, Dario; Brasca, Maria Gabriella; Festuccia, Claudio; Fiorentini, Francesco; Locatelli, Giuseppe; Pastori, Wilma; et al From Molecular Cancer Therapeutics (2010), 9(8), 2243-2254.
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