Vinorelbine(Navelbine)/

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Vinorelbine(Navelbine)/

Vinorelbine(Navelbine)/

Cat.No.ABP000672 Chemical NameVinorelbine(Navelbine)/ CAS71486-22-1 MDL: MFCD00866248 MolFormulaC45H54N4O8 MolWeight778.942 Purity >99%

Chemical Name : Vinorelbine(Navelbine)/

CAS : 71486-22-1

Synonyms: VINORELBINE

Storage:at -20℃ 2 years

Biologieal

Vinorelbine is the first 5´NOR semi-synthetic vinca alkaloid and an anti-mitotic chemotherapy drug. [1][2] In the breast cancer cell lines MCF-7 and MDA-MB-468, increased p38 activity was demonstrated following vinorelbine but not doxorubicin treatment, whether vinorelbine was given prior to or simultaneously with doxorubicin. Mitogen-activated protein kinase (MAPK) activity and p53 expression remained unchanged following vinorelbine treatment. [3]

Reference

[1] http://en.wikipedia.org/wiki/Vinorelbine

[2] Ngan VK et al. Cancer Res. 2000 Sep 15;60(18):5045-51

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