Mifepristone(Mifeprex)/

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Mifepristone(Mifeprex)/

Mifepristone(Mifeprex)/

Cat.No.ABP000437 Chemical NameMifepristone(Mifeprex)/ CAS84371-65-3 MDL: MFCD18380790 MolFormulaC29H32D3NO2 MolWeight432.619 Purity >99%

Chemical Name : Mifepristone(Mifeprex)/

CAS : 84371-65-3

Synonyms: MIFEPRISTONE-D3

Storage:at -20℃ 2 years

Biologieal

Mifepristone(Mifeprex) is a synthetic steroid compound used as a pharmaceutical. It is used as abortifacient in the first two months of pregnancy, and in smaller doses it is used as an emergency contraceptive. [1]In the presence of progesterone, it acts as a competitive progesterone receptor antagonist (in the absence of progesterone, mifepristone acts as a partial agonist). It is a 19-nor steroid with a bulky p-(dimethylamino)phenyl substituent above the plane of the molecule at the 11β-position responsible for inducing or stabilizing an inactive receptor conformation and a hydrophobic 1-propynyl substituent below the plane of the molecule at the 17α-position that increases its progesterone receptor binding affinity.

Reference

[1] http://en.wikipedia.org/wiki/Mifepristone

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