Chemical Name : PLX-4032(RG7204)/PLX4032
CAS : 1029872-54-5
Storage:at -20℃ 2 years
PLX4032 is a highly selective inhibitor of BRAF kinase activity, with an IC50 of 44 nmol/L against V600E-mutant BRAF.  BRAFV600E cancer-causing mutation occurs in most melanomas and about eight percent of all solid tumors. 
BRAF mutant melanoma cell strains were highly sensitive to PLX4032 with IC50 in the nM range (60–450 nM), whereas BRAF wild-type cells were resistant, with IC50 2.4 μM or above.