MGCD-265/MGCD265

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MGCD-265/MGCD265

MGCD-265/MGCD265

Cat.No.ABP000138 Chemical NameMGCD-265/MGCD265 CAS875337-44-3 MDL: MFCD17779287 MolFormulaC26H20FN5O2S2 MolWeight517.607 Purity >99%

Chemical Name : MGCD-265/MGCD265

CAS : 875337-44-3

Synonyms: MGCD-265

Solubility:DMSO

Storage:at -20℃ 2 years

Biologieal

MGCD265 is a tyrosine kinase inhibitor that targets the MET, VEGFR-1, VEGFR-2, VEGFR-3, RON and TIE2 receptor tyrosine kinases, which appear to play key roles in tumour development and blood vessel formation (angiogenesis) and tumour survival. MGCD265 is currently in phase I single-agent clinical trials for solid tumour cancers and in phase II trials for solid tumours and NSCLC .

Reference

[1] Cañadas I et al. Clin Transl Oncol. 2010 Apr;12(4):253-60

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