67469-78-7

Vanoxerine(GBR-12909) /

67469-78-7

Cat.No.ABP000311 Chemical NameVanoxerine(GBR-12909) / MDL: MFCD00055193 MolFormulaC28H32F2N2O.2ClH MolWeight523.492 Purity 99%

Chemical Name : Vanoxerine(GBR-12909) /

CAS : 67469-78-7

Synonyms: VANOXERINE DIHYDROCHLORIDE

Storage:at -20℃ 2 years

Biologieal

Vanoxerine (GBR-12909) is a piperazine derivative which is a potent and selective DRI (dopamine reuptake inhibitor). GBR-12909 binds to the target site on the DAT ~ 500 times more strongly than cocaine, but simultaneously inhibits the release of dopamine. This combined effect only slightly elevates dopamine levels, giving vanoxerine only mild stimulant effects. Vanoxerine has been researched for use in treating cocaine dependence both as a substitute for cocaine and to block the rewarding effects.

Reference

[1] http://en.wikipedia.org/wiki/Vanoxerine

[2] http://koso.ucsd.edu/~martin/YoungGBR12909.pdf

Enquiry