660-27-5

 Home / Products / Others / 660-27-5
Diisopropylammonium dichloroacetate/

660-27-5

Cat.No.ABP000811 Chemical NameDiisopropylammonium dichloroacetate/ MDL: MFCD00868288 MolFormulaC6H15N.C2H2Cl2O2 MolWeight230.133 Purity >98%

Chemical Name : Diisopropylammonium dichloroacetate/

CAS : 660-27-5

Synonyms: DIISOPROPYLAMMONIUM DICHLOROACETATE

Solubility:Soluble to 100 mM in DMSO

Storage:Desiccate at +4°C

Biologieal

CB2 antagonist/inverse agonist (Ki = 31.2 nM) that displays 165-fold selectivity over CB1 receptors. Behaves as a weak partial/inverse agonist at CB1 receptors.

Reference

Hosohata et al (1997) AM630 is a competitive cannabinoid receptor antagonist in the guinea pig brain. Life Sci. 61 PL115. PMID: 9284087.

Hosohata et al (1997) AM630 antagonism of cannabinoid-stimulated [35S]GTPγS binding in the mouse brain. Eur.J.Pharmacol. 321 R1. PMID: 9083796.

Landsman et al (1998) AM630 is an inverse agonist at the human cannabinoid CB1 receptor. Life Sci. 62 PL109. PMID: 9496703.

Enquiry