475150-69-7

BAN ORL 24HCL

475150-69-7

Cat.No.ABP000130 Chemical NameBAN ORL 24HCL MolFormulaC27H35N3O2 MolWeight433.5857 Purity >98%

Chemical Name : BAN ORL 24HCL

CAS : 475150-69-7

Synonyms: (2R)-1-Benzyl-N-(3-spiro[isobenzofuran-1(3H),4'-piperidin]-1'-ylpropyl)-2-pyrrolidinecarboxamide

Solubility:H2O, DMSO and EtOH

Storage:at -20℃ 2 years

Biologieal

Highly potent and selective NOP receptor antagonist (IC50: 0.27 nM); more than 2500 fold selective over other opioid receptors

Reference

Y Goto et al. Identification of a novel spiropiperidine opioid receptor-like 1 antagonist class by a focused library approach featuring 3D-pharmacophore similarity. J. Med. Chem. 2006, 49 847-849.
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