38234-21-8

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Fertirelin/

38234-21-8

Cat.No.ABP000197 Chemical NameFertirelin/ MDL: MFCD00133495 MolFormulaC55H76N16O12 MolWeight1153.31 Purity >98%

Chemical Name : Fertirelin/

CAS : 38234-21-8

Synonyms: FERTIRELIN

Storage:at -20℃ 2 months

Biologieal

Fertirelin is a synthetic luteinizing hormone-releasing hormone (LH-RH) analogue, and it is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis. [1]
Fertirelin was administered at the beginning of the protocol followed 7 days later by 500 μg cloprosterol. Two days later, a second dose of fertirelin was given and AI performed 16-19 h later regardless of the incidence of behavioral oestrus. The conception rate did not differ between the 50 μg fertirelin group (61.1%; n = 72) and the 100 μg group (59.5%; n = 42; NS). [2]


 

Reference

[1] Nappier JL et al. J Agric Food Chem, 1998, 46 (11),4563–7

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